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    Results: 1 to 20 of 78287

    1.
    Full record GDS6248

    Diet-induced obesity model: liver

    Analysis of livers of C57BL/6J mice fed a high fat diet for up to 24 weeks. Significant body weight gain was observed after 4 weeks. Results provide insight into the effect of high fat diets on metabolism in the liver.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, transformed count, 3 protocol, 9 time sets
    Platform:
    GPL6887
    Series:
    GSE39549
    51 Samples
    Download data:
    GEO
    2.
    Full record GDS6247

    Diet-induced obesity model: white adipose tissue

    Analysis of epididymal and mesenteric white adipose tissues (WAT) of mice fed a high fat diet for up to 24 weeks. Excessive fat accumulation was evident in visceral WAT depots after 4 weeks. Results provide insight into the molecular events that occur during the development of diet-induced obesity.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, transformed count, 2 protocol, 5 time, 2 tissue sets
    Platform:
    GPL6887
    Series:
    GSE39549
    40 Samples
    Download data:
    GEO
    3.
    Full record GDS6176

    Caspase-1 deficiency effect on lipid-loaded intestines

    Analysis of the epithelial layer of intestine from Casp1-null, C57BL/6 males 2 hours after an oral lipid bolus. Caspase-1 activates the proinflammatory cytokines IL-1β and IL-18. These results, together with those from GDS4922, provide insight into the role of caspase-1 in lipid metabolism.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, transformed count, 2 genotype/variation, 3 tissue sets
    Platform:
    GPL11533
    Series:
    GSE32515
    18 Samples
    Download data:
    GEO (CEL)
    4.
    Full record GDS6000

    High-fat diet effect on brown adipose tissue development

    Analysis of interscapular brown adipose tissues from mice fed a high fat diet for up to 24 weeks. Results compared to those from epididymal white adipose tissues (GDS6247) in order to provide insight into the effect of high-fat diets on the development of brown and white adipose tissues.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, transformed count, 2 protocol, 6 time sets
    Platform:
    GPL6887
    Series:
    GSE64718
    33 Samples
    Download data:
    GEO
    DataSet
    Accession:
    GDS6000
    ID:
    6000
    5.
    Full record GDS5881

    Nebulin deficiency effect on the soleus

    Analysis of soleus muscles from 6 week old males with a conditional knockout of nebulin in their striated muscles. Nebulin is a giant filamentous protein that is coextensive with actin filaments of the skeletal muscle sarcomere. Results provide insight into the role of nebulin in adult muscles.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 genotype/variation sets
    Platform:
    GPL6246
    Series:
    GSE70213
    12 Samples
    Download data:
    GEO (CEL)
    6.
    Full record GDS5880

    Nebulin deficiency effect on the quadriceps

    Analysis of quadriceps muscles from 6 week old males with a conditional knockout of nebulin in their striated muscles. Nebulin is a giant filamentous protein that is coextensive with actin filaments of the skeletal muscle sarcomere. Results provide insight into the role of nebulin in adult muscles.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 genotype/variation sets
    Platform:
    GPL6246
    Series:
    GSE70213
    12 Samples
    Download data:
    GEO (CEL)
    7.
    Full record GDS5824

    Short-term high fat diet effect on epididymal adipose fractions: time course

    Analysis of primary adipocytes from epididymis of C57BL/6J males fed a 60% high fat diet (HFD) for up to 7 days to induce obesity. Results provide insight into the molecular mechanisms underlying insulin resistance in adipose tissues during early obesity.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 protocol, 3 time, 2 tissue sets
    Platform:
    GPL6246
    Series:
    GSE65557
    18 Samples
    Download data:
    GEO (CEL)
    8.
    Full record GDS5808

    Type I angiotensin II receptor antagonist valsartan effect on mitral regurgitation males: left atria

    Analysis of left atria of mitral regurgitation (MR) males treated with valsartan one week before surgery and then daily after surgery. Valsartan is a type I angiotensin II receptor blocker. Results provide insight into molecular mechanisms underlying atrial myocardial remodeling in MR subjects.
    Organism:
    Sus scrofa
    Type:
    Expression profiling by array, count, 2 agent, 2 stress sets
    Platform:
    GPL3533
    Series:
    GSE43072
    6 Samples
    Download data:
    GEO (CEL)
    DataSet
    Accession:
    GDS5808
    ID:
    5808
    9.
    Full record GDS5673

    Glucagon effect on hepatocytes deficient in lysine acetyltransferase 2B or WD repeat-containing protein 5

    Analysis of C57BL6/J primary hepatocytes depleted of either lysine acetyltransferase 2B (KAT2B) or WD repeat-containing protein 5 (WDR5) via shRNA knockdown, then stimulated with glucagon for 90 minutes. Results provide insight into the roles of KAT2B and WDR5 in hepatic gluconeogenesis.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 agent, 3 genotype/variation sets
    Platform:
    GPL6246
    Series:
    GSE47179
    10 Samples
    Download data:
    GEO (CEL, CHP)
    10.
    Full record GDS5654

    Subcutaneous and visceral adipose tissues

    Analysis of adipose tissue from two subcutaneous depots (inguinal and axillary) and two visceral depots (epididymal and mesenteric) from age-matched, C57Bl/6 males. SubQ and VISC represent two broad categories of obesity. Results provide insight into fat depot-specific molecular profiles.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 4 other, 2 tissue sets
    Platform:
    GPL8321
    Series:
    GSE53307
    12 Samples
    Download data:
    GEO (CEL)
    11.
    Full record GDS5651

    DNA methyltransferase inhibitor 5-Aza-2’deoxycytidine effect on partially-ligated left carotid artery

    Analysis of arteries from C57BL/6 males pretreated with DNMT inhibitor 5Aza for 2 wk, then subjected to partial carotid ligation (PCL) and continued 5Aza treatment for 1 wk after ligation. PCL induces disturbed blood flow. Results provide insight into molecular basis of atherosclerosis development.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 agent, 2 protocol, 2 tissue sets
    Platform:
    GPL6887
    Series:
    GSE56143
    12 Samples
    Download data:
    GEO
    12.
    Full record GDS5648

    Chronic high-calorie diet effect on Kras-driven lung tumors

    Analysis of lung tumors isolated from mice that develop KRAS-driven lung tumors. The KrasG12D mice were fed a high-calorie diet (HCD) starting 12 wk before tumor induction; tumors were collected 11 wk after tumor induction. Results provide insight into HCD effects on KRAS-driven lung tumorigenesis.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 growth protocol sets
    Platform:
    GPL6887
    Series:
    GSE56260
    11 Samples
    Download data:
    GEO
    13.
    Full record GDS5520

    Rosiglitazone effect on adipose progenitor cells

    Analysis of adipose progenitor cells from animals fed a diet supplemented with rosiglitazone (ROS) for 2 months. ROS is a thiazolidinedione antidiabetic drug. Results provide insight into the effect of chronic ROS administration on the stem cell properties of adipose progenitor cells.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 agent sets
    Platform:
    GPL6887
    Series:
    GSE30116
    6 Samples
    Download data:
    GEO
    14.
    Full record GDS5469

    Left ventricle myocardium from MerCreMer model of transient cardiomyopathy: time course

    Temporal analysis of left ventricle myocardium from the MCM model of cardiomyopathy. Transient cardiomyopathy develops in this model after 5 day exposure to tamoxifen, with peak heart failure (HF) at day 10, and resolved HF at day 28. Results provide insight into the molecular basis of evolving HF.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 4 disease state, 5 protocol, 5 time sets
    Platform:
    GPL6885
    Series:
    GSE54681
    19 Samples
    Download data:
    GEO
    15.
    Full record GDS5438

    Lung from cigarette smoke-related chronic obstructive pulmonary disease model: time course

    Analysis of lung from cigarette smoke (CS)-treated C57BL/6N females at 4 and 6 months of age. Tobacco smoking is a major cause of chronic obstructive pulmonary disease (COPD). Results provide insight into the molecular mechanisms underlying cigarette smoke-induced COPD.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 age, 2 stress sets
    Platform:
    GPL6885
    Series:
    GSE52509
    12 Samples
    Download data:
    GEO
    DataSet
    Accession:
    GDS5438
    ID:
    5438
    16.
    Full record GDS5435

    Dietary palatinose effect on liver

    Analysis of liver from C57Bl/6J males fed isocaloric diets containing sucrose or palatinose. Sucrose is a high glycemic index (GI) sugar; palatinose is a low GI sugar. Results provide insight into molecular mechanisms underlying the role of sucrose in the development of non-alcoholic fatty liver.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 protocol sets
    Platform:
    GPL6885
    Series:
    GSE54723
    14 Samples
    Download data:
    GEO
    DataSet
    Accession:
    GDS5435
    ID:
    5435
    17.
    Full record GDS5425

    Monoacylglycerol acyltransferase 1 deficiency effect on high-fat diet fed mice: liver

    Analysis of liver from diet-induced obese males depleted for monoacylglycerol acyltransferase 1 (Mogat1) via intraperitoneal injections of antisense oligonucleotide directed against Mogat1. Results provide insight into the role of Mogat1 in the development of nonalcoholic steatohepatitis (NASH).
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 genotype/variation sets
    Platform:
    GPL6887
    Series:
    GSE60349
    8 Samples
    Download data:
    GEO
    18.
    Full record GDS5390

    Whey protein hydrolysate diet effect on exercised epitrochlearis muscle

    Analysis of epitrochlearis muscle from males exercised for 2hr then fed a whey protein hydrolysate (WPH) diet or a control diet with an identical amino acid composition (AAM). Results provide insight into the molecular basis of the greater post-exercise muscle protein synthesis in the WPH group.
    Organism:
    Rattus norvegicus
    Type:
    Expression profiling by array, transformed count, 2 protocol sets
    Platform:
    GPL1355
    Series:
    GSE49486
    8 Samples
    Download data:
    GEO (CEL)
    DataSet
    Accession:
    GDS5390
    ID:
    5390
    19.
    Full record GDS5377

    Folate deficiency effect on methylenetetrahydrofolate reductase MTHFR+/- intestinal neoplasia model: duodenum

    Analysis of intestine from MTHFR+/- BALB/c mice fed a low folate diet (0.3mg/kg) for 1 yr. The MTHFR C677T polymorphism is associated with risk for colorectal cancer. Results provide insight into mechanisms underlying the impact of folate and MTHFR deficiency on tumorigenesis.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets
    Platform:
    GPL6246
    Series:
    GSE34011
    8 Samples
    Download data:
    GEO (CEL)
    DataSet
    Accession:
    GDS5377
    ID:
    5377
    20.
    Full record GDS5345

    Dietary vitamin D3 supplementation effect on hippocampus: dose effect

    Analysis of hippocampus from F344 rats fed dietary supplement of cholecalciferol (vitamin D3) at doses of 10,000, 1000 and 100 IU/kg diet for 18 weeks. Results provide insight into molecular mechanisms underlying vitamin D-mediated synaptic function enhancement.
    Organism:
    Rattus norvegicus
    Type:
    Expression profiling by array, transformed count, 3 dose sets
    Platform:
    GPL6247
    Series:
    GSE61326
    26 Samples
    Download data:
    GEO (CEL)

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      db=gds|term=(smok*%20OR%20diet)%20AND%20(mammals[organism]%20NOT%20human[organism])|query=1|qty=50|blobid=NCID_1_124879879_130.14.18.34_9001_1511347441_1553803582_0MetA0_S_MegaStore_F_1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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