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    Results: 1 to 20 of 266

    1.
    Full record GDS4992

    Cholestatic intestinal injury model: jejunum

    Analysis of jejunum from AJ and C57BL6J males with common bile duct ligation (CBDL). The two strains demonstrate different rates of cholestasis-related bacterial translocation and mortality. Results provide insight into molecular pathways underlying intestinal injury following cholestasis.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, transformed count, 2 protocol, 2 strain sets
    Platform:
    GPL6246
    Series:
    GSE47099
    12 Samples
    Download data:
    GEO (CEL)
    2.
    Full record GDS4930

    Fetal lung development

    Analysis of lung tissues at 53 to 154 days post conception. Results provide insight into the molecular regulation of lung development.
    Organism:
    Homo sapiens
    Type:
    Expression profiling by array, transformed count, 29 time sets
    Platform:
    GPL570
    Series:
    GSE14334
    38 Samples
    Download data:
    GEO (CEL)
    3.
    Full record GDS4223

    Simian Immunodeficiency Virus infection effect on lymph nodes of Sooty mangabeys and Rhesus macaques

    Temporal analysis of lymph nodes of SIVsmm infected Sooty mangabeys (SM) and SIVmac239 infected Rhesus macaques (RM). SIVsmm is non-pathogenic to host SM but origin of pathogens (HIV-2/SIVmac) to humans and RM. Results provide insight into the molecular basis of the differences in host responses.
    Organism:
    Cercocebus atys; Macaca mulatta
    Type:
    Expression profiling by array, count, 3 disease state, 3 infection, 2 species, 3 time sets
    Platform:
    GPL3535
    Series:
    GSE17626
    28 Samples
    Download data:
    GEO (CEL)
    4.
    Full record GDS3556

    Torcetrapib effect on adrenal carcinoma cell line

    Analysis of H295 adrenal carcinoma cells treated with torcetrapib, an anti-cholesterol drug. Adverse side effects of torcetrapib treatment include changes in blood pressure, potassium, sodium, and aldosterone. Results provide insight into the molecular basis of the off-target side effects.
    Organism:
    Homo sapiens
    Type:
    Expression profiling by array, transformed count, 3 agent sets
    Platform:
    GPL570
    Series:
    GSE15918
    9 Samples
    Download data:
    GEO (CEL)
    DataSet
    Accession:
    GDS3556
    ID:
    3556
    5.
    Full record GDS3190

    Macrophage response to lipopolysaccharide and interleukin-10 co-treatment: time course

    Analysis of interleukin-10 (IL-10)-deficient macrophages at various time points up to 30 minutes following co-stimulation with lipopolysaccharide (LPS) and IL-10. LPS elicits an inflammatory response. Results provide insight into molecular mechanisms underlying the anti-inflammatory effect of IL-10.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 agent, 3 time sets
    Platform:
    GPL1261
    Series:
    GSE9509
    18 Samples
    Download data:
    GEO (CEL)
    DataSet
    Accession:
    GDS3190
    ID:
    3190
    6.
    Full record GDS1989

    Melanoma progression

    Analysis of tissue specimens representing benign nevus, atypical nevus, melanoma in situ, vertical growth phase (VGP) melanoma, and metastatic growth phase (MGP) melanoma. Results identify expression signatures that distinguish benign and atypical nevi and melanomas in situ from VGPs and MGPs.
    Organism:
    Homo sapiens
    Type:
    Expression profiling by array, count, 7 disease state, 4 specimen sets
    Platform:
    GPL570
    Series:
    GSE4587
    18 Samples
    Download data:
    GEO
    DataSet
    Accession:
    GDS1989
    ID:
    1989
    7.
    Full record GDS1850

    Carious pulpal tissue

    Expression profiling of core pulpal tissue from carious teeth. RNA pooled from 11 carious teeth. Results provide insight into the molecular events that occur during the progression of dental caries.
    Organism:
    Homo sapiens
    Type:
    Expression profiling by array, count, 2 disease state sets
    Platform:
    GPL96
    Series:
    GSE1629
    4 Samples
    Download data:
    GEO
    DataSet
    Accession:
    GDS1850
    ID:
    1850
    8.

    Dynamic Patterns of Threat-associated Gene Expression in the Amygdala and Blood

    (Submitter supplied) Purpose: Identification the biological response to fear and stress in both brain and blood is vital for investigators performing peripheral studies of psychiatric traits. The goal of this study was to determine genes responsive to fear conditioning (FC), a well-characterized rodent model of threat-exposure, in the presence or absence of prior stress history, providing insight into the physiological processes underlying traumatic memory formation and trauma-related disorders such as PTSD. more...
    Organism:
    Mus musculus
    Type:
    Expression profiling by high throughput sequencing
    Platform:
    GPL15103
    30 Samples
    Download data:
    GEO (TXT), SRA SRP152146
    Series
    Accession:
    GSE116630
    ID:
    200116630
    9.

    UGA Folic acid supplementation in pregnant women

    (Submitter supplied) DNA samples were derived from maternal blood collected during a baseline prenatal visit and at delivery.
    Organism:
    Homo sapiens
    Type:
    Methylation profiling by genome tiling array
    Platform:
    GPL13534
    47 Samples
    Download data:
    GEO (IDAT)
    Series
    Accession:
    GSE114935
    ID:
    200114935
    10.

    DNA methylation and inflammation marker profiles associated with a history of depression.

    (Submitter supplied) Depression is a common and disabling disorder, representing a major social and economic health issue. Moreover, depression is associated with the progression of diseases with an inflammatory etiology including many inflammatory-related disorders. At the molecular level, the mechanisms by which depression might promote the onset of these diseases and associated immune-dysfunction are not well understood. more...
    Organism:
    Homo sapiens
    Type:
    Methylation profiling by genome tiling array
    Platform:
    GPL13534
    194 Samples
    Download data:
    GEO (CSV)
    Series
    Accession:
    GSE113725
    ID:
    200113725
    11.

    Identification and single cell functional characterization of an endodermally-biased pluripotent sub-state in human embryonic stem cells

    (Submitter supplied) Human embryonic stem cells (hESC) display substantial heterogeneity in gene expression, implying the existence of discrete substates within the stem cell compartment. To determine whether these substates impact fate decisions of hESC we used a GFP reporter line to investigate the properties of fractions of putative undifferentiated cells defined by their differential expression of the endoderm transcription factor, GATA6, together with the hESC surface marker, SSEA3. more...
    Organism:
    Homo sapiens
    Type:
    Expression profiling by high throughput sequencing
    Platform:
    GPL16791
    4 Samples
    Download data:
    GEO (TSV), SRA SRP140469
    Series
    Accession:
    GSE113168
    ID:
    200113168
    12.

    Gene expression analysis in PKP2mut cardiomyocytes

    (Submitter supplied) In the present study, genome-wide expression profiling was carried out to identify genes dysregulated in PKP2mut-iPSCs-derived cardiomyocytes.
    Organism:
    Homo sapiens
    Type:
    Expression profiling by array
    Platform:
    GPL14550
    6 Samples
    Download data:
    GEO (TXT)
    Series
    Accession:
    GSE98525
    ID:
    200098525
    13.

    DNA Methylation Signatures of Crohn's disease Largely a Consequence of Inflammation

    (Submitter supplied) Crohn’s disease is a relapsing inflammatory disorder with a variable clinical course. While most patients present with purely an inflammatory phenotype (B1) at diagnosis, a subgroup (~20%) rapidly progresses to complicated disease manifestations that include stricturing (B2) within 5 years. DNA methylation is a key epigenetic mechanism that can regulate gene expression and thereby influence the development and progression of complex diseases. more...
    Organism:
    Homo sapiens
    Type:
    Methylation profiling by array
    Platform:
    GPL21145
    402 Samples
    Download data:
    GEO (TXT)
    Series
    Accession:
    GSE112611
    ID:
    200112611
    14.

    Emory University African American Microbiome in Pregnancy Cohort

    (Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
    Organism:
    Homo sapiens
    Type:
    Expression profiling by array; Methylation profiling by genome tiling array
    Platforms:
    GPL13534 GPL10558
    537 Samples
    Download data:
    GEO (IDAT)
    Series
    Accession:
    GSE107460
    ID:
    200107460
    15.

    Emory University African American Microbiome in Pregnancy Cohort [Methylation]

    (Submitter supplied) All subjects were enrolled from Grady Memorial and Emory Midtown Hospitals. Subjects provided blood samples at two timepoints during pregnancy. Medical record abstraction was used to determine the presence of fetal intolerance of labor.
    Organism:
    Homo sapiens
    Type:
    Methylation profiling by genome tiling array
    Platform:
    GPL13534
    127 Samples
    Download data:
    GEO (IDAT)
    Series
    Accession:
    GSE107459
    ID:
    200107459
    16.

    Emory University African American Microbiome in Pregnancy Cohort [expression]

    (Submitter supplied) All subjects were enrolled from Grady Memorial and Emory Midtown Hospitals. Subjects provided blood samples at two timepoints during pregnancy. Medical record abstraction was used to determine the presence of fetal intolerance of labor.
    Organism:
    Homo sapiens
    Type:
    Expression profiling by array
    Platform:
    GPL10558
    410 Samples
    Download data:
    GEO (IDAT)
    Series
    Accession:
    GSE107437
    ID:
    200107437
    17.

    Biogeographic conservation and CO2-dynamics of the cytosine methylome in the globally important cyanobacterium Trichodesmium [WGBS]

    (Submitter supplied) Our paper presents the results of a study in which we used whole genome bisulfite sequencing (WGBS), RNA-Seq (i.e. transcriptomics), high-CO2 physiology experiments, and spatiotemporally separated samples isolated in situ (i.e. directly from the ocean) to examine the metabolic potential of genome-wide cytosine (5mC) methylation (i.e. epigenomics), its potential impacts to transcriptional dynamics under both present-day and future ocean acidification conditions, and its biogeographic conservation in the globally-significant, biogeochemically-critical marine cyanobacterium Trichodesmium.
    Organism:
    Trichodesmium erythraeum IMS101; Trichodesmium; Trichodesmium erythraeum 21-75; Trichodesmium thiebautii VI-1
    Type:
    Methylation profiling by high throughput sequencing
    4 related Platforms
    11 Samples
    Download data:
    GEO (FA, TXT), SRA SRP089989
    Series
    Accession:
    GSE86979
    ID:
    200086979
    18.

    Biogeographic conservation and CO2-dynamics of the cytosine methylome in the globally important cyanobacterium Trichodesmium

    (Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
    Organism:
    Trichodesmium erythraeum 21-75; Trichodesmium thiebautii VI-1; Trichodesmium; Trichodesmium erythraeum IMS101
    Type:
    Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
    5 related Platforms
    15 Samples
    Download data:
    GEO (TXT)
    Series
    Accession:
    GSE86992
    ID:
    200086992
    19.

    Biogeographic conservation and CO2-dynamics of the cytosine methylome in the globally important cyanobacterium Trichodesmium [RNA-Seq]

    (Submitter supplied) Our paper presents the results of a study in which we used whole genome bisulfite sequencing (WGBS), RNA-Seq (i.e. transcriptomics), high-CO2 physiology experiments, and spatiotemporally separated samples isolated in situ (i.e. directly from the ocean) to examine the metabolic potential of genome-wide cytosine (5mC) methylation (i.e. epigenomics), its potential impacts to transcriptional dynamics under both present-day and future ocean acidification conditions, and its biogeographic conservation in the globally-significant, biogeochemically-critical marine cyanobacterium Trichodesmium.
    Organism:
    Trichodesmium erythraeum IMS101
    Type:
    Expression profiling by high throughput sequencing
    Platform:
    GPL22446
    4 Samples
    Download data:
    GEO (TXT), SRA SRP089988
    Series
    Accession:
    GSE86991
    ID:
    200086991
    20.

    mRNA-Seq profiling SIX2+ and Foxd1+ cells in mouse embryonic and SIX2+ and SIX2-/MEIS1+ cells human fetal kidney

    (Submitter supplied) To characterize the molecular features of human and mouse nephron progenitors and stromal cells we performed intracellular labeling for SIX2 and/or MEIS1 antibodies, FACS, and RNA-seq. Mouse interstitial progenitors were isolated by Foxd1-Tdt transgenic line, FACS, and RNA-seq
    Organism:
    Homo sapiens
    Type:
    Expression profiling by high throughput sequencing
    Platform:
    GPL18573
    20 Samples
    Download data:
    GEO (TXT), SRA SRP114780
    Series
    Accession:
    GSE102230
    ID:
    200102230

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