Logo of acsmedlettACS PublicationsThis JournalSearchSubmit a manuscript
ACS Med Chem Lett

Volume 9(7);  2018 Jul 12

Articles from this journal are generally available in PMC after a 12-month delay (embargo); however, the delay may vary at the discretion of the publisher.

Editorial

Bruce E. Maryanoff
ACS Med Chem Lett. 2018 Jul 12; 9(7): 575. Published online 2018 Jul 12. doi: 10.1021/acsmedchemlett.8b00207
PMCID:
PMC6047019

In This Issue

Lorraine F. Clark
ACS Med Chem Lett. 2018 Jul 12; 9(7): 576. Published online 2018 Jul 12. doi: 10.1021/acsmedchemlett.8b00299
PMCID:
PMC6047037

Letters

Laurent Knerr, Fabrizio Giordanetto, Peter Nordberg, Daniel Pettersen, Nidhal Selmi, Hans-Georg Beisel, Hannah de la Motte, Thomas Olsson, Tim D. J. Perkins, Margareta Herslöf, Åsa Månsson, Mikael Dahlström, Ingemar Starke, Johan Broddefalk, Gabrielle Saarinen, Fredrik Klingegård, Eva Hurt-Camejo, Birgitta Rosengren, Johan Brengdahl, Frank Jansen, Mattias Rohman, Jenny Sandmark, Kenth Hallberg, Tomas Åkerud, Robert G. Roth, Marie Ahlqvist
ACS Med Chem Lett. 2018 Jul 12; 9(7): 594–599. Published online 2018 Jun 23. doi: 10.1021/acsmedchemlett.7b00505
PMCID:
PMC6047051
Fabrizio Giordanetto, Laurent Knerr, Peter Nordberg, Daniel Pettersen, Nidhal Selmi, Hans-Georg Beisel, Hannah de la Motte, Åsa Månsson, Mikael Dahlström, Johan Broddefalk, Gabrielle Saarinen, Fredrik Klingegård, Eva Hurt-Camejo, Birgitta Rosengren, Johannes Wikström, Maria Wågberg, Johan Brengdahl, Mattias Rohman, Jenny Sandmark, Tomas Åkerud, Robert G. Roth, Frank Jansen, Marie Ahlqvist
ACS Med Chem Lett. 2018 Jul 12; 9(7): 600–605. Published online 2018 Jun 23. doi: 10.1021/acsmedchemlett.7b00507
PMCID:
PMC6047026
Satish K. Chitneni, Hai Yan, Michael R. Zalutsky
ACS Med Chem Lett. 2018 Jul 12; 9(7): 606–611. Published online 2018 May 1. doi: 10.1021/acsmedchemlett.7b00478
PMCID:
PMC6047021
Zahid Q. Bonday, Guillermo S. Cortez, Michael J. Grogan, Stephen Antonysamy, Ken Weichert, Wayne P. Bocchinfuso, Fengling Li, Steven Kennedy, Binghui Li, Mary M. Mader, Cheryl H. Arrowsmith, Peter J. Brown, Mohammad S. Eram, Magdalena M. Szewczyk, Dalia Barsyte-Lovejoy, Masoud Vedadi, Ernesto Guccione, Robert M. Campbell
ACS Med Chem Lett. 2018 Jul 12; 9(7): 612–617. Published online 2018 Apr 23. doi: 10.1021/acsmedchemlett.8b00014
PMCID:
PMC6047023
Thumuganti Gayathri, Santosh Karnewar, Srigiridhar Kotamraju, Surya Prakash Singh
ACS Med Chem Lett. 2018 Jul 12; 9(7): 618–622. Published online 2018 Jun 20. doi: 10.1021/acsmedchemlett.8b00022
PMCID:
PMC6047038
Hilary Schenck Eidam, John Russell, Kaushik Raha, Michael DeMartino, Donghui Qin, Huiping Amy Guan, Zhiliu Zhang, Gong Zhen, Haiyu Yu, Chengde Wu, Yan Pan, Gerard Joberty, Nico Zinn, Sylvie Laquerre, Sharon Robinson, Angela White, Amanda Giddings, Ehsan Mohammadi, Beverly Greenwood-Van Meerveld, Allen Oliff, Sanjay Kumar, Mui Cheung
ACS Med Chem Lett. 2018 Jul 12; 9(7): 623–628. Published online 2018 May 24. doi: 10.1021/acsmedchemlett.8b00035
PMCID:
PMC6047170
Jelena Konstantinović, Milica Videnović, Stefania Orsini, Katarina Bogojević, Sarah D’Alessandro, Diletta Scaccabarozzi, Nataša Terzić Jovanović, Luigi Gradoni, Nicoletta Basilico, Bogdan A. Šolaja
ACS Med Chem Lett. 2018 Jul 12; 9(7): 629–634. Published online 2018 May 4. doi: 10.1021/acsmedchemlett.8b00053
PMCID:
PMC6047044
Yi Liao, Liping Xu, Siyu Ou, Holly Edwards, Daniel Luedtke, Yubin Ge, Zhihui Qin
ACS Med Chem Lett. 2018 Jul 12; 9(7): 635–640. Published online 2018 Jun 13. doi: 10.1021/acsmedchemlett.8b00057
PMCID:
PMC6047035
Yuko Nishiyama, Shuichi Mori, Makoto Makishima, Shinya Fujii, Hiroyuki Kagechika, Yuichi Hashimoto, Minoru Ishikawa
ACS Med Chem Lett. 2018 Jul 12; 9(7): 641–645. Published online 2018 Jun 23. doi: 10.1021/acsmedchemlett.8b00058
PMCID:
PMC6047039
Pierpaolo Calandro, Giulia Iovenitti, Claudio Zamperini, Francesca Candita, Elena Dreassi, Mario Chiariello, Adriano Angelucci, Silvia Schenone, Maurizio Botta, Arianna Mancini
ACS Med Chem Lett. 2018 Jul 12; 9(7): 646–651. Published online 2018 May 7. doi: 10.1021/acsmedchemlett.8b00062
PMCID:
PMC6047171
Douglas C. Beshore, Christina N. Di Marco, Ronald K. Chang, Thomas J. Greshock, Lei Ma, Marion Wittmann, Matthew A. Seager, Kenneth A. Koeplinger, Charles D. Thompson, Joy Fuerst, George D. Hartman, Mark T. Bilodeau, William J. Ray, Scott D. Kuduk
ACS Med Chem Lett. 2018 Jul 12; 9(7): 652–656. Published online 2018 Apr 30. doi: 10.1021/acsmedchemlett.8b00095
PMCID:
PMC6047034
Carrie L. Lomelino, Akilah B. Murray, Claudiu T. Supuran, Robert McKenna
ACS Med Chem Lett. 2018 Jul 12; 9(7): 657–661. Published online 2018 May 10. doi: 10.1021/acsmedchemlett.8b00100
PMCID:
PMC6047028
Renjitha Jalaja, Shyni G. Leela, Praveen K. Valmiki, Chettiyan Thodi F. Salfeena, Kizhakkan T. Ashitha, Venkata Rao D. Krishna Rao, Mangalam S. Nair, Raghu K. Gopalan, Sasidhar B. Somappa
ACS Med Chem Lett. 2018 Jul 12; 9(7): 662–666. Published online 2018 Jun 18. doi: 10.1021/acsmedchemlett.8b00109
PMCID:
PMC6047173
Jinwoo Kim, Jin Soo Shin, Sunjoo Ahn, Soo Bong Han, Young-Sik Jung
ACS Med Chem Lett. 2018 Jul 12; 9(7): 667–672. Published online 2018 Apr 13. doi: 10.1021/acsmedchemlett.8b00134
PMCID:
PMC6047043
Jon J. Hangeland, Lynn M. Abell, Leonard P. Adam, Ji Jiang, Todd J. Friends, Lauren E. Haque, James Neels, Joelle M. Onorato, Alice Ye A. Chen, David S. Taylor, Xiaohong Yin, Thomas W. Harrity, Michael D. Basso, Richard Yang, Paul G. Sleph, David A. Gordon, Christine S. Huang, Ruth R. Wexler, Heather J. Finlay, R. Michael Lawrence
ACS Med Chem Lett. 2018 Jul 12; 9(7): 673–678. Published online 2018 Jun 15. doi: 10.1021/acsmedchemlett.8b00138
PMCID:
PMC6047032
Xianhai Huang, Jason Brubaker, Wei Zhou, Purakkattle J. Biju, Li Xiao, Ning Shao, Ying Huang, Li Dong, Zhidan Liu, Rema Bitar, Alexei Buevich, Joon Jung, Scott L. Peterson, John W. Butcher, Joshua Close, Michelle Martinez, Rachel N. MacCoss, Hongjun Zhang, Scott Crawford, Kevin D. McCormick, Robert Aslanian, Ravi Nargund, Craig Correll, Francois Gervais, Hongchen Qiu, Xiaoxin Yang, Charles Garlisi, Diane Rindgen, Kevin M. Maloney, Phieng Siliphaivanh, Anandan Palani
ACS Med Chem Lett. 2018 Jul 12; 9(7): 679–684. Published online 2018 Jun 23. doi: 10.1021/acsmedchemlett.8b00145
PMCID:
PMC6047040
Helen Y. Chen, Christopher W. Plummer, Dong Xiao, Harry R. Chobanian, Duane DeMong, Michael Miller, Maria E. Trujillo, Melissa Kirkland, Daniel Kosinski, Joel Mane, Michele Pachanski, Boonlert Cheewatrakoolpong, Jerry Di Salvo, Brande Thomas-Fowlkes, Sarah Souza, Daniel A. Tatosian, Qing Chen, Michael J. Hafey, Robert Houle, Andrew F. Nolting, Robert Orr, Juliann Ehrhart, Adam B. Weinglass, Richard Tschirret-Guth, Andrew D. Howard, Steven L. Colletti
ACS Med Chem Lett. 2018 Jul 12; 9(7): 685–690. Published online 2018 Jun 14. doi: 10.1021/acsmedchemlett.8b00149
PMCID:
PMC6047031
Linah N. Rusere, Ashley N. Matthew, Gordon J. Lockbaum, Muhammad Jahangir, Alicia Newton, Christos J. Petropoulos, Wei Huang, Nese Kurt Yilmaz, Celia A. Schiffer, Akbar Ali
ACS Med Chem Lett. 2018 Jul 12; 9(7): 691–696. Published online 2018 May 17. doi: 10.1021/acsmedchemlett.8b00150
PMCID:
PMC6047049
Madher N. AlFindee, Yagya P. Subedi, Mariana C. Fiori, Srinivasan Krishnan, Abbey Kjellgren, Guillermo A. Altenberg, Cheng-Wei T. Chang
ACS Med Chem Lett. 2018 Jul 12; 9(7): 697–701. Published online 2018 Jun 19. doi: 10.1021/acsmedchemlett.8b00158
PMCID:
PMC6047172
William M. Huggins, William T. Barker, James T. Baker, Nicholas A. Hahn, Roberta J. Melander, Christian Melander
ACS Med Chem Lett. 2018 Jul 12; 9(7): 702–707. Published online 2018 May 25. doi: 10.1021/acsmedchemlett.8b00161
PMCID:
PMC6047036
Kiran V. Mahasenan, Derong Ding, Ming Gao, Trung T. Nguyen, Mark A. Suckow, Valerie A. Schroeder, William R. Wolter, Mayland Chang, Shahriar Mobashery
ACS Med Chem Lett. 2018 Jul 12; 9(7): 708–713. Published online 2018 Jun 11. doi: 10.1021/acsmedchemlett.8b00163
PMCID:
PMC6047167
Sara R. Goldstein, Chen Liu, Martin K. Safo, Akito Nakagawa, Warren M. Zapol, Jeffrey D. Winkler
ACS Med Chem Lett. 2018 Jul 12; 9(7): 714–718. Published online 2018 May 11. doi: 10.1021/acsmedchemlett.8b00166
PMCID:
PMC6047046
Sida Shen, Xiangyu He, Zheng Yang, Liang Zhang, Yingtao Liu, Zhiyuan Zhang, Weiwei Wang, Wei Liu, Yufeng Li, Dong Huang, Kai Sun, Xiaojing Ni, Xu Yang, Xinxin Chu, Yumin Cui, Qiang Lv, Jiong Lan, Fusheng Zhou
ACS Med Chem Lett. 2018 Jul 12; 9(7): 719–724. Published online 2018 Jun 25. doi: 10.1021/acsmedchemlett.8b00167
PMCID:
PMC6047022
Claudia Melis, Simona Distinto, Giulia Bianco, Rita Meleddu, Filippo Cottiglia, Benedetta Fois, Domenico Taverna, Rossella Angius, Stefano Alcaro, Francesco Ortuso, Marco Gaspari, Andrea Angeli, Sonia Del Prete, Clemente Capasso, Claudiu T. Supuran, Elias Maccioni
ACS Med Chem Lett. 2018 Jul 12; 9(7): 725–729. Published online 2018 Jun 6. doi: 10.1021/acsmedchemlett.8b00170
PMCID:
PMC6047168
Nadia R. Ayat, Jing-Can Qin, Han Cheng, Sarah Roelle, Songqi Gao, Yajuan Li, Zheng-Rong Lu
ACS Med Chem Lett. 2018 Jul 12; 9(7): 730–735. Published online 2018 Jun 6. doi: 10.1021/acsmedchemlett.8b00172
PMCID:
PMC6047029
Lara S. Kallander, David Washburn, Mark A. Hilfiker, Hilary Schenck Eidam, Brian G. Lawhorn, Joanne Prendergast, Ryan Fox, Sarah Dowdell, Sharada Manns, Tram Hoang, Steve Zhao, Guosen Ye, Marlys Hammond, Dennis A. Holt, Theresa Roethke, Xuan Hong, Robert A. Reid, Robert Gampe, Hong Zhang, Elsie Diaz, Alan R. Rendina, Amy M. Quinn, Bob Willette
ACS Med Chem Lett. 2018 Jul 12; 9(7): 736–740. Published online 2018 Jul 2. doi: 10.1021/acsmedchemlett.8b00173
PMCID:
PMC6047045
Linhu Li, Kai Lv, Yupeng Yang, Jingquan Sun, Zeyu Tao, Apeng Wang, Bin Wang, Hongjian Wang, Yunhe Geng, Mingliang Liu, Huiyuan Guo, Yu Lu
ACS Med Chem Lett. 2018 Jul 12; 9(7): 741–745. Published online 2018 Jun 26. doi: 10.1021/acsmedchemlett.8b00177
PMCID:
PMC6047030
Qian Zhao, James R. Manning, James Sutton, Abran Costales, Martin Sendzik, Cynthia M. Shafer, Julian R. Levell, Gang Liu, Thomas Caferro, Young Shin Cho, Mark Palermo, Gregg Chenail, Julia Dooley, Brian Villalba, Ali Farsidjani, Jinyun Chen, Stephanie Dodd, Ty Gould, Guiqing Liang, Kelly Slocum, Minying Pu, Brant Firestone, Joseph Growney, Tycho Heimbach, Raymond Pagliarini
ACS Med Chem Lett. 2018 Jul 12; 9(7): 746–751. Published online 2018 Jun 11. doi: 10.1021/acsmedchemlett.8b00182
PMCID:
PMC6047033
Jeffrey C. Pelletier, Suzie Chen, Haiyan Bian, Raj Shah, Garry R. Smith, Jay E. Wrobel, Allen B. Reitz
ACS Med Chem Lett. 2018 Jul 12; 9(7): 752–756. Published online 2018 Jun 15. doi: 10.1021/acsmedchemlett.8b00189
PMCID:
PMC6047042
Sean P. Brown, Paul Dransfield, Marc Vimolratana, Liusheng Zhu, Jian Luo, Jane Zhang, XianYun Jiao, Vatee Pattaropong, Simon Wong, Run Zhuang, Gayathri Swaminath, Jonathan B. Houze, Daniel C.-H. Lin
ACS Med Chem Lett. 2018 Jul 12; 9(7): 757–760. Published online 2018 Jun 6. doi: 10.1021/acsmedchemlett.8b00213
PMCID:
PMC6047174
Sobhana Babu Boga, Yongqi Deng, Liang Zhu, Yang Nan, Alan B. Cooper, Gerald W. Shipps, Jr., Ronald Doll, Neng-Yang Shih, Hugh Zhu, Robert Sun, Tong Wang, Sunil Paliwal, Hon-Chung Tsui, Xiaolei Gao, Xin Yao, Jagdish Desai, James Wang, Abdul Basit Alhassan, Joseph Kelly, Mehul Patel, Kiran Muppalla, Subrahmanyam Gudipati, Li-Kang Zhang, Alexei Buevich, David Hesk, Donna Carr, Priya Dayananth, Stuart Black, Hong Mei, Kathleen Cox, Bradley Sherborne, Alan W. Hruza, Li Xiao, Weihong Jin, Brian Long, Gongjie Liu, Stacey A. Taylor, Paul Kirschmeier, William T. Windsor, Robert Bishop, Ahmed A. Samatar
ACS Med Chem Lett. 2018 Jul 12; 9(7): 761–767. Published online 2018 Jun 14. doi: 10.1021/acsmedchemlett.8b00220
PMCID:
PMC6047169

Patent Highlight

Benjamin E. Blass
ACS Med Chem Lett. 2018 Jul 12; 9(7): 587–589. Published online 2018 May 14. doi: 10.1021/acsmedchemlett.8b00178
PMCID:
PMC6047041
Robert B. Kargbo
ACS Med Chem Lett. 2018 Jul 12; 9(7): 590–591. Published online 2018 May 22. doi: 10.1021/acsmedchemlett.8b00216
PMCID:
PMC6047020
Robert B. Kargbo
ACS Med Chem Lett. 2018 Jul 12; 9(7): 592–593. Published online 2018 Jun 28. doi: 10.1021/acsmedchemlett.8b00273
PMCID:
PMC6047025

Technology Note

Brian P. David, Oleksii Dubrovskyi, Thomas E. Speltz, Jeremy J. Wolff, Jonna Frasor, Laura M. Sanchez, Terry W. Moore
ACS Med Chem Lett. 2018 Jul 12; 9(7): 768–772. Published online 2018 May 17. doi: 10.1021/acsmedchemlett.8b00091
PMCID:
PMC6047048
Rui Zhang, Guoqing Li, Michael Wismer, Petr Vachal, Steven L. Colletti, Zhi-Cai Shi
ACS Med Chem Lett. 2018 Jul 12; 9(7): 773–777. Published online 2018 May 7. doi: 10.1021/acsmedchemlett.8b00183
PMCID:
PMC6047024

Viewpoints

Esben M. Bech, Søren L. Pedersen, Knud J. Jensen
ACS Med Chem Lett. 2018 Jul 12; 9(7): 577–580. Published online 2018 Jun 15. doi: 10.1021/acsmedchemlett.8b00226
PMCID:
PMC6047018
Victoria A. Steadman
ACS Med Chem Lett. 2018 Jul 12; 9(7): 581–583. Published online 2018 Jun 4. doi: 10.1021/acsmedchemlett.8b00236
PMCID:
PMC6047047
Lyn H. Jones
ACS Med Chem Lett. 2018 Jul 12; 9(7): 584–586. Published online 2018 Jun 27. doi: 10.1021/acsmedchemlett.8b00276
PMCID:
PMC6047027

Articles from ACS Medicinal Chemistry Letters are provided here courtesy of American Chemical Society