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1.

An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance.

Bester AC, Lee JD, Chavez A, Lee YR, Nachmani D, Vora S, Victor J, Sauvageau M, Monteleone E, Rinn JL, Provero P, Church GM, Clohessy JG, Pandolfi PP.

Cell. 2018 Apr 19;173(3):649-664.e20. doi: 10.1016/j.cell.2018.03.052.

PMID:
29677511
2.

Canadian cod comeback derailed.

Rowe S, Rose GA.

Nature. 2018 Apr;556(7702):436. doi: 10.1038/d41586-018-04898-4. No abstract available.

PMID:
29679035
3.

Herpes genitalis and the philosopher's stance.

Dunphy K.

J Med Ethics. 2014 Dec;40(12):793-7. doi: 10.1136/medethics-2012-100894. Epub 2014 Jan 15.

PMID:
24429670
4.

Draft genome sequence of Camellia sinensis var. sinensis provides insights into the evolution of the tea genome and tea quality.

Wei C, Yang H, Wang S, Zhao J, Liu C, Gao L, Xia E, Lu Y, Tai Y, She G, Sun J, Cao H, Tong W, Gao Q, Li Y, Deng W, Jiang X, Wang W, Chen Q, Zhang S, Li H, Wu J, Wang P, Li P, Shi C, Zheng F, Jian J, Huang B, Shan D, Shi M, Fang C, Yue Y, Li F, Li D, Wei S, Han B, Jiang C, Yin Y, Xia T, Zhang Z, Bennetzen JL, Zhao S, Wan X.

Proc Natl Acad Sci U S A. 2018 Apr 20. pii: 201719622. doi: 10.1073/pnas.1719622115. [Epub ahead of print]

PMID:
29678829
5.

SAMHD1 acts at stalled replication forks to prevent interferon induction.

Coquel F, Silva MJ, Técher H, Zadorozhny K, Sharma S, Nieminuszczy J, Mettling C, Dardillac E, Barthe A, Schmitz AL, Promonet A, Cribier A, Sarrazin A, Niedzwiedz W, Lopez B, Costanzo V, Krejci L, Chabes A, Benkirane M, Lin YL, Pasero P.

Nature. 2018 Apr 18. doi: 10.1038/s41586-018-0050-1. [Epub ahead of print]

PMID:
29670289
6.

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.

Guo L, Kim HJ, Wang H, Monaghan J, Freyermuth F, Sung JC, O'Donovan K, Fare CM, Diaz Z, Singh N, Zhang ZC, Coughlin M, Sweeny EA, DeSantis ME, Jackrel ME, Rodell CB, Burdick JA, King OD, Gitler AD, Lagier-Tourenne C, Pandey UB, Chook YM, Taylor JP, Shorter J.

Cell. 2018 Apr 19;173(3):677-692.e20. doi: 10.1016/j.cell.2018.03.002.

PMID:
29677512
7.

Prognostic Significance of Nuisance Bleeding in Anticoagulated Patients with Atrial Fibrillation.

O'Brien EC, Holmes DN, Thomas LE, Fonarow GC, Allen LA, Gersh BJ, Kowey PR, Singer DE, Ezekowitz MD, Naccarelli GV, Ansell JE, Chan PS, Mahaffey KW, Go AS, Freeman JV, Reiffel JA, Peterson ED, Piccini JP, Hylek EM.

Circulation. 2018 Apr 20. pii: CIRCULATIONAHA.117.031354. doi: 10.1161/CIRCULATIONAHA.117.031354. [Epub ahead of print]

PMID:
29678813
8.

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms.

Liu TL, Upadhyayula S, Milkie DE, Singh V, Wang K, Swinburne IA, Mosaliganti KR, Collins ZM, Hiscock TW, Shea J, Kohrman AQ, Medwig TN, Dambournet D, Forster R, Cunniff B, Ruan Y, Yashiro H, Scholpp S, Meyerowitz EM, Hockemeyer D, Drubin DG, Martin BL, Matus DQ, Koyama M, Megason SG, Kirchhausen T, Betzig E.

Science. 2018 Apr 20;360(6386). pii: eaaq1392. doi: 10.1126/science.aaq1392.

PMID:
29674564
9.

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq.

Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, van Galen P, Bonal DM, Nguyen QD, Beck A, Sinai C, Czech T, Dorfer C, Goumnerova L, Lavarino C, Carcaboso AM, Mora J, Mylvaganam R, Luo CC, Peyrl A, Popović M, Azizi A, Batchelor TT, Frosch MP, Martinez-Lage M, Kieran MW, Bandopadhayay P, Beroukhim R, Fritsch G, Getz G, Rozenblatt-Rosen O, Wucherpfennig KW, Louis DN, Monje M, Slavc I, Ligon KL, Golub TR, Regev A, Bernstein BE, Suvà ML.

Science. 2018 Apr 20;360(6386):331-335. doi: 10.1126/science.aao4750.

PMID:
29674595
10.

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.

Hofweber M, Hutten S, Bourgeois B, Spreitzer E, Niedner-Boblenz A, Schifferer M, Ruepp MD, Simons M, Niessing D, Madl T, Dormann D.

Cell. 2018 Apr 19;173(3):706-719.e13. doi: 10.1016/j.cell.2018.03.004.

PMID:
29677514
11.
12.

GPR68 Senses Flow and Is Essential for Vascular Physiology.

Xu J, Mathur J, Vessières E, Hammack S, Nonomura K, Favre J, Grimaud L, Petrus M, Francisco A, Li J, Lee V, Xiang FL, Mainquist JK, Cahalan SM, Orth AP, Walker JR, Ma S, Lukacs V, Bordone L, Bandell M, Laffitte B, Xu Y, Chien S, Henrion D, Patapoutian A.

Cell. 2018 Apr 19;173(3):762-775.e16. doi: 10.1016/j.cell.2018.03.076.

PMID:
29677517
13.

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia.

Thompson AA, Walters MC, Kwiatkowski J, Rasko JEJ, Ribeil JA, Hongeng S, Magrin E, Schiller GJ, Payen E, Semeraro M, Moshous D, Lefrere F, Puy H, Bourget P, Magnani A, Caccavelli L, Diana JS, Suarez F, Monpoux F, Brousse V, Poirot C, Brouzes C, Meritet JF, Pondarré C, Beuzard Y, Chrétien S, Lefebvre T, Teachey DT, Anurathapan U, Ho PJ, von Kalle C, Kletzel M, Vichinsky E, Soni S, Veres G, Negre O, Ross RW, Davidson D, Petrusich A, Sandler L, Asmal M, Hermine O, De Montalembert M, Hacein-Bey-Abina S, Blanche S, Leboulch P, Cavazzana M.

N Engl J Med. 2018 Apr 19;378(16):1479-1493. doi: 10.1056/NEJMoa1705342.

PMID:
29669226
14.
15.

Development and Evaluation of an Optimal Human Single-Chain Variable Fragment-Derived BCMA-Targeted CAR T Cell Vector.

Smith EL, Staehr M, Masakayan R, Tatake IJ, Purdon TJ, Wang X, Wang P, Liu H, Xu Y, Garrett-Thomson SC, Almo SC, Riviere I, Liu C, Brentjens RJ.

Mol Ther. 2018 Mar 28. pii: S1525-0016(18)30143-6. doi: 10.1016/j.ymthe.2018.03.016. [Epub ahead of print]

PMID:
29678657
16.

A probiotic modulates the microbiome and immunity in multiple sclerosis.

Tankou SK, Regev K, Healy BC, Tjon E, Laghi L, Cox LM, Kivisäkk P, Pierre IV, Lokhande H, Gandhi R, Cook S, Glanz B, Stankiewicz J, Weiner HL.

Ann Neurol. 2018 Apr 20. doi: 10.1002/ana.25244. [Epub ahead of print]

PMID:
29679417
17.

Ketogenic diet, high intensity interval training (HIIT) and memory training in the treatment of mild cognitive impairment: A case study.

Dahlgren K, Gibas KJ.

Diabetes Metab Syndr. 2018 Apr 11. pii: S1871-4021(18)30116-4. doi: 10.1016/j.dsx.2018.04.031. [Epub ahead of print]

PMID:
29678606
18.

Use of two gRNAs for CRISPR/Cas9 improves bi-allelic homologous recombination efficiency in mouse embryonic stem cells.

Acosta S, Fiore L, Carota IA, Oliver G.

Genesis. 2018 Apr 20. doi: 10.1002/dvg.23212. [Epub ahead of print]

PMID:
29676032
19.

Update on Systemic Prostate Cancer Therapies: Management of Metastatic Castration-resistant Prostate Cancer in the Era of Precision Oncology.

Nuhn P, De Bono JS, Fizazi K, Freedland SJ, Grilli M, Kantoff PW, Sonpavde G, Sternberg CN, Yegnasubramanian S, Antonarakis ES.

Eur Urol. 2018 Apr 16. pii: S0302-2838(18)30246-X. doi: 10.1016/j.eururo.2018.03.028. [Epub ahead of print] Review.

PMID:
29673712
20.

CRISPR/Cas9 for cancer research and therapy.

Zhan T, Rindtorff N, Betge J, Ebert MP, Boutros M.

Semin Cancer Biol. 2018 Apr 16. pii: S1044-579X(17)30274-2. doi: 10.1016/j.semcancer.2018.04.001. [Epub ahead of print] Review.

PMID:
29673923
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