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Sterol methyltransferase a target for anti-amoeba therapy: Towards transition state analog and suicide substrate drug design.

Kidane ME, Vanderloop BH, Zhou W, Thomas CD, Ramos E, Singha U, Chaudhuri M, Nes WD.

J Lipid Res. 2017 Oct 17. pii: jlr.M079418. doi: 10.1194/jlr.M079418. [Epub ahead of print]


Biomechanical testing of the calcified metacarpal articular surface and its association with subchondral bone microstructure in Thoroughbred racehorses.

Williamson AJ, Sims NA, Thomas CDL, Lee PVS, Stevenson MA, Whitton RC.

Equine Vet J. 2017 Aug 21. doi: 10.1111/evj.12748. [Epub ahead of print]


Lacunar-canalicular network in femoral cortical bone is reduced in aged women and is predominantly due to a loss of canalicular porosity.

Ashique AM, Hart LS, Thomas CDL, Clement JG, Pivonka P, Carter Y, Mousseau DD, Cooper DML.

Bone Rep. 2017 Jun 28;7:9-16. doi: 10.1016/j.bonr.2017.06.002. eCollection 2017 Dec.


Climate change vulnerability for species-Assessing the assessments.

Wheatley CJ, Beale CM, Bradbury RB, Pearce-Higgins JW, Critchlow R, Thomas CD.

Glob Chang Biol. 2017 Sep;23(9):3704-3715. doi: 10.1111/gcb.13759. Epub 2017 Jun 29.


Looking for the Most Suitable Orthotopic Retinoblastoma Mouse Model in Order to Characterize the Tumoral Development.

Lemaitre S, Poyer F, Marco S, Fréneaux P, Doz F, Aerts I, Desjardins L, Cassoux N, Thomas CD.

Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):3055-3064. doi: 10.1167/iovs.17-21760.


Climate change, climatic variation and extreme biological responses.

Palmer G, Platts PJ, Brereton T, Chapman JW, Dytham C, Fox R, Pearce-Higgins JW, Roy DB, Hill JK, Thomas CD.

Philos Trans R Soc Lond B Biol Sci. 2017 Jun 19;372(1723). pii: 20160144. doi: 10.1098/rstb.2016.0144.


Pharmacokinetics of Escalating Doses of Oral Psilocybin in Healthy Adults.

Brown RT, Nicholas CR, Cozzi NV, Gassman MC, Cooper KM, Muller D, Thomas CD, Hetzel SJ, Henriquez KM, Ribaudo AS, Hutson PR.

Clin Pharmacokinet. 2017 Mar 28. doi: 10.1007/s40262-017-0540-6. [Epub ahead of print]


Determining Whether the Impacts of Introduced Species Are Negative Cannot Be Based Solely on Science: A Response to Russell and Blackburn.

Tassin J, Thompson K, Carroll SP, Thomas CD.

Trends Ecol Evol. 2017 Apr;32(4):230-231. doi: 10.1016/j.tree.2017.02.001. Epub 2017 Feb 27. No abstract available.


Retraction of the Research Article: "Individualistic sensitivities and exposure to climate change explain variation in species' distribution and abundance changes".

Palmer G, Hill JK, Brereton TM, Brooks DR, Chapman JW, Fox R, Oliver TH, Thomas CD.

Sci Adv. 2016 Apr 29;2(4):e1600819. doi: 10.1126/sciadv.1600819. eCollection 2016 Apr.


Structures of replication initiation proteins from staphylococcal antibiotic resistance plasmids reveal protein asymmetry and flexibility are necessary for replication.

Carr SB, Phillips SE, Thomas CD.

Nucleic Acids Res. 2016 Mar 18;44(5):2417-28. doi: 10.1093/nar/gkv1539. Epub 2016 Jan 20.


Three-dimensional reconstruction of Haversian systems in human cortical bone using synchrotron radiation-based micro-CT: morphology and quantification of branching and transverse connections across age.

Maggiano IS, Maggiano CM, Clement JG, Thomas CD, Carter Y, Cooper DM.

J Anat. 2016 May;228(5):719-32. doi: 10.1111/joa.12430. Epub 2016 Jan 7.


Individualistic sensitivities and exposure to climate change explain variation in species' distribution and abundance changes.

Palmer G, Hill JK, Brereton TM, Brooks DR, Chapman JW, Fox R, Oliver TH, Thomas CD.

Sci Adv. 2015 Oct 30;1(9):e1400220. doi: 10.1126/sciadv.1400220. eCollection 2015 Oct. Retraction in: Palmer G, Hill JK, Brereton TM, Brooks DR, Chapman JW, Fox R, Oliver TH, Thomas CD. Sci Adv. 2016 Apr;2(4):e1600819.


The Anthropocene Speciation Hypothesis Remains Valid: Reply to Hulme et al.

Thomas CD.

Trends Ecol Evol. 2015 Nov;30(11):636-8. doi: 10.1016/j.tree.2015.09.008. Epub 2015 Oct 22. No abstract available.


Does 3D orientation account for variation in osteon morphology assessed by 2D histology?

Hennig C, Thomas CD, Clement JG, Cooper DM.

J Anat. 2015 Oct;227(4):497-505. doi: 10.1111/joa.12357. Epub 2015 Aug 7.


Macro- and microclimatic interactions can drive variation in species' habitat associations.

Pateman RM, Thomas CD, Hayward SA, Hill JK.

Glob Chang Biol. 2016 Feb;22(2):556-66. doi: 10.1111/gcb.13056. Epub 2015 Nov 26.


Hydrologically driven ecosystem processes determine the distribution and persistence of ecosystem-specialist predators under climate change.

Carroll MJ, Heinemeyer A, Pearce-Higgins JW, Dennis P, West C, Holden J, Wallage ZE, Thomas CD.

Nat Commun. 2015 Jul 31;6:7851. doi: 10.1038/ncomms8851.


Rapid acceleration of plant speciation during the Anthropocene.

Thomas CD.

Trends Ecol Evol. 2015 Aug;30(8):448-55. doi: 10.1016/j.tree.2015.05.009. Epub 2015 Jun 23.


Two Species with an Unusual Combination of Traits Dominate Responses of British Grasshoppers and Crickets to Environmental Change.

Beckmann BC, Purse BV, Roy DB, Roy HE, Sutton PG, Thomas CD.

PLoS One. 2015 Jun 25;10(6):e0130488. doi: 10.1371/journal.pone.0130488. eCollection 2015.


Refugia and connectivity sustain amphibian metapopulations afflicted by disease.

Heard GW, Thomas CD, Hodgson JA, Scroggie MP, Ramsey DS, Clemann N.

Ecol Lett. 2015 Aug;18(8):853-63. doi: 10.1111/ele.12463. Epub 2015 Jun 25.


Reply to Hulme et al.: Cover of non-native species is too low to adversely affect native plant diversity at a national scale.

Thomas CD, Palmer G.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):E2990. doi: 10.1073/pnas.1507966112. Epub 2015 Jun 1. No abstract available.

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