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Connecting genetic risk to disease end points through the human blood plasma proteome.

Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M, Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J.

Nat Commun. 2017 Feb 27;8:14357. doi: 10.1038/ncomms14357.


Fit for the Eye: Aptamers in Ocular Disorders.

Drolet DW, Green LS, Gold L, Janjic N.

Nucleic Acid Ther. 2016 Jun;26(3):127-46. doi: 10.1089/nat.2015.0573. Epub 2016 Jan 12. Review.


SELEX: How It Happened and Where It will Go.

Gold L.

J Mol Evol. 2015 Dec;81(5-6):140-3. doi: 10.1007/s00239-015-9705-9. Epub 2015 Oct 20. No abstract available.


Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy.

Hathout Y, Brody E, Clemens PR, Cripe L, DeLisle RK, Furlong P, Gordish-Dressman H, Hache L, Henricson E, Hoffman EP, Kobayashi YM, Lorts A, Mah JK, McDonald C, Mehler B, Nelson S, Nikrad M, Singer B, Steele F, Sterling D, Sweeney HL, Williams S, Gold L.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7153-8. doi: 10.1073/pnas.1507719112. Epub 2015 May 26.


Systematic selection of modified aptamer pairs for diagnostic sandwich assays.

Ochsner UA, Green LS, Gold L, Janjic N.

Biotechniques. 2014 Mar 1;56(3):125-8, 130, 132-3. doi: 10.2144/000114134. eCollection 2014.


Beyond antibodies: new affinity reagents to unlock the proteome.

Lollo B, Steele F, Gold L.

Proteomics. 2014 Mar;14(6):638-44. doi: 10.1002/pmic.201300187. Epub 2014 Feb 20.


Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.

Davies DR, Gelinas AD, Zhang C, Rohloff JC, Carter JD, O'Connell D, Waugh SM, Wolk SK, Mayfield WS, Burgin AB, Edwards TE, Stewart LJ, Gold L, Janjic N, Jarvis TC.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):19971-6. doi: 10.1073/pnas.1213933109. Epub 2012 Nov 8.


The sweet allure of XNA.

Steele FR, Gold L.

Nat Biotechnol. 2012 Jul 10;30(7):624-5. doi: 10.1038/nbt.2298. No abstract available.


Life's simple measures: unlocking the proteome.

Brody E, Gold L, Mehan M, Ostroff R, Rohloff J, Walker J, Zichi D.

J Mol Biol. 2012 Oct 5;422(5):595-606. doi: 10.1016/j.jmb.2012.06.021. Epub 2012 Jun 19.


Aptamers and the RNA world, past and present.

Gold L, Janjic N, Jarvis T, Schneider D, Walker JJ, Wilcox SK, Zichi D.

Cold Spring Harb Perspect Biol. 2012 Mar 1;4(3). pii: a003582. doi: 10.1101/cshperspect.a003582. Review.


Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer.

Ostroff RM, Bigbee WL, Franklin W, Gold L, Mehan M, Miller YE, Pass HI, Rom WN, Siegfried JM, Stewart A, Walker JJ, Weissfeld JL, Williams S, Zichi D, Brody EN.

PLoS One. 2010 Dec 7;5(12):e15003. doi: 10.1371/journal.pone.0015003.


Aptamer-based multiplexed proteomic technology for biomarker discovery.

Gold L, Ayers D, Bertino J, Bock C, Bock A, Brody EN, Carter J, Dalby AB, Eaton BE, Fitzwater T, Flather D, Forbes A, Foreman T, Fowler C, Gawande B, Goss M, Gunn M, Gupta S, Halladay D, Heil J, Heilig J, Hicke B, Husar G, Janjic N, Jarvis T, Jennings S, Katilius E, Keeney TR, Kim N, Koch TH, Kraemer S, Kroiss L, Le N, Levine D, Lindsey W, Lollo B, Mayfield W, Mehan M, Mehler R, Nelson SK, Nelson M, Nieuwlandt D, Nikrad M, Ochsner U, Ostroff RM, Otis M, Parker T, Pietrasiewicz S, Resnicow DI, Rohloff J, Sanders G, Sattin S, Schneider D, Singer B, Stanton M, Sterkel A, Stewart A, Stratford S, Vaught JD, Vrkljan M, Walker JJ, Watrobka M, Waugh S, Weiss A, Wilcox SK, Wolfson A, Wolk SK, Zhang C, Zichi D.

PLoS One. 2010 Dec 7;5(12):e15004. doi: 10.1371/journal.pone.0015004.


High-content affinity-based proteomics: unlocking protein biomarker discovery.

Brody EN, Gold L, Lawn RM, Walker JJ, Zichi D.

Expert Rev Mol Diagn. 2010 Nov;10(8):1013-22. doi: 10.1586/erm.10.89. Review.


Theoretical principles of in vitro selection using combinatorial nucleic acid libraries.

Vant-Hull B, Gold L, Zichi DA.

Curr Protoc Nucleic Acid Chem. 2000 Feb;Chapter 9:Unit 9.1. doi: 10.1002/0471142700.nc0901s00.


A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment.

Daniels DA, Chen H, Hicke BJ, Swiderek KM, Gold L.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15416-21. Epub 2003 Dec 15.


Aptamers as therapeutic and diagnostic agents.

Brody EN, Gold L.

J Biotechnol. 2000 Mar;74(1):5-13. Review.


The use of aptamers in large arrays for molecular diagnostics.

Brody EN, Willis MC, Smith JD, Jayasena S, Zichi D, Gold L.

Mol Diagn. 1999 Dec;4(4):381-8.


RNA aptamers to the peptidyl transferase inhibitor chloramphenicol.

Burke DH, Hoffman DC, Brown A, Hansen M, Pardi A, Gold L.

Chem Biol. 1997 Nov;4(11):833-43.


Post-SELEX combinatorial optimization of aptamers.

Eaton BE, Gold L, Hicke BJ, Janjić N, Jucker FM, Sebesta DP, Tarasow TM, Willis MC, Zichi DA.

Bioorg Med Chem. 1997 Jun;5(6):1087-96.

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